Influence of non-invasive ventilation combined with moxifloxacin on the prognosis of patients with chronic obstructive pulmonary disease and respiratory failure
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摘要: 目的 探讨无创通气联合莫西沙星对慢性阻塞性肺病合并呼吸衰竭患者预后的影响.方法 选取72例慢性阻塞性肺病合并呼吸衰竭患者,随机分为观察组(常规治疗+无创通气+莫西沙星)和对照组(常规治疗+无创通气).比较2组患者预后指标的改善情况.结果 观察组总有效率、细菌清除率、pH、p(C02)、p(02)、FEV1、APACHEⅡ、生活质量评分均显著优于对照组(P＜0.05).结论 无创通气联合莫西沙星治疗慢性阻塞性肺病合并呼吸衰竭患者疗效显著.Abstract: Objective To explore the influence of non-invasive ventilation combined with moxifloxacin on the prognosis of patients with chronic obstructive pulmonary disease and respiratory failure.Methods A total of 72 patients with chronic obstructive pulmonary disease and respiratory failure were randomly divided into observation group (non-invasive ventilation plus conventional therapy plus moxifloxacin) and control group (conventional treatment plus non-invasive ventilation).Indexes of prognosis were compared.Results After treatment,the total effective rate,bacteria clear rate,pH,p(CO2),p(O2),FEV1,APACHE Ⅱ and quality of life in the observation group were significantly better than those in the control group (P ＜ 0.05).Conclusion Non-invasive ventilation combined with moxifloxacin is effective in treatment of patients with chronic obstructive pulmonary disease and respiratory failure.
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期刊类型引用(5)
1. 杨艳，马希刚，余红波. 经鼻高流量湿化氧疗联合莫西沙星溶液雾化吸入在慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭中的疗效观察. 宁夏医学杂志. 2024(08): 684-687 . 
百度学术
2. 董健. 慢性阻塞性肺疾病患者应用莫西沙星治疗的疗效及预后探究. 中国社区医师. 2020(08): 21+23 . 百度学术
3. 吴涛. 莫西沙星溶液雾化吸入治疗慢阻肺合并呼吸衰竭的临床疗效. 中国合理用药探索. 2019(08): 1930-1932+1936 . 百度学术
4. 陈宏，翟金健，曹克军. 无创通气在ICU治疗COPD合并重度CO_2潴留的疗效分析. 中国继续医学教育. 2017(19): 102-103 . 百度学术
5. 谢轶群，韩林华，邹华丽. 中西医结合治疗慢性阻塞性肺病致呼吸衰竭患者的疗效观察. 临床合理用药杂志. 2017(35): 35-36 . 百度学术
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