Objective To evaluate the influencing factors of aspiration in neurological critically ill patients by Meta-analysis.
Methods PubMed, Embase, Web of Science, CNKI, and Wanfang Data were searched from inception to 1 October, 2023, to obtain relevant studies on influencing factors of aspiration in neurological critically ill patients. The literature screening, data extraction and quality evaluation were completed by two researchers. RevMan 5.4 and Stata 13.0 software were applied for pooled Meta-analysisand assessed publication bias, respectively.
Results A total of 8 articles, including 1, 315 neurocritical care patients, were included in this study. Nine influencing factors related to aspiration were extracted for Meta-analysis. The Meta-analysis results showed that the three influencing factors that caused aspiration in neurocritical care patients were stroke history (OR=5.03, 95%CI, 2.71 to 9.32, P < 0.000 01), National Institutes of Health Stroke Scale (NIHSS) score >10 (OR=3.35, 95%CI, 1.75 to 6.42, P=0.000 3), and gastric residual volume >150 mL (OR=7.13, 95%CI, 2.55 to 9.96, P=0.001).
Conclusion This study provides a scientific basis for clinical healthcare professionals to early identify high-risk patients for aspiration, take targeted intervention measures, and prevent the occurrence of aspiration.
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