Influencing factors of aspiration in neurological critically ill patients: a Meta-analysis

ZHANG Yang; DIAO Haiqing; Li Mengyue; TIAN Ting; LIU Xiaoguang; MA Qiang; LU Guangyu; YU Hailong; LI Yuping

doi:10.7619/jcmp.20242193

Journal of Clinical Medicine in Practice > 2025 > 29(1): 118-124. > DOI: 10.7619/jcmp.20242193

ZHANG Yang, DIAO Haiqing, Li Mengyue, TIAN Ting, LIU Xiaoguang, MA Qiang, LU Guangyu, YU Hailong, LI Yuping. Influencing factors of aspiration in neurological critically ill patients: a Meta-analysis[J]. Journal of Clinical Medicine in Practice, 2025, 29(1): 118-124. DOI: 10.7619/jcmp.20242193

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Influencing factors of aspiration in neurological critically ill patients: a Meta-analysis

ZHANG Yang¹,
DIAO Haiqing¹,
Li Mengyue¹,
TIAN Ting²,
LIU Xiaoguang^{3, 4},
MA Qiang^{3, 4},
LU Guangyu²,
YU Hailong^{4, 5},
LI Yuping^{3, 4,}

1.
School of Nursing, Yangzhou University, Yangzhou, Jiangsu, 225009
2.
School of Public Health, Yangzhou University, Yangzhou, Jiangsu, 225009
3.
Neurosurgery Department, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, Jiangsu, 225001
4.
Neurocritical Care Unit, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, Jiangsu, 225001
5.
Neurology Department, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, Jiangsu, 225001

More Information

Received Date: May 23, 2024
Revised Date: June 25, 2024

Graphical Abstract

Abstract

Abstract

Objective
To evaluate the influencing factors of aspiration in neurological critically ill patients by Meta-analysis.
Methods
PubMed, Embase, Web of Science, CNKI, and Wanfang Data were searched from inception to 1 October, 2023, to obtain relevant studies on influencing factors of aspiration in neurological critically ill patients. The literature screening, data extraction and quality evaluation were completed by two researchers. RevMan 5.4 and Stata 13.0 software were applied for pooled Meta-analysisand assessed publication bias, respectively.
Results
A total of 8 articles, including 1, 315 neurocritical care patients, were included in this study. Nine influencing factors related to aspiration were extracted for Meta-analysis. The Meta-analysis results showed that the three influencing factors that caused aspiration in neurocritical care patients were stroke history (OR=5.03, 95%CI, 2.71 to 9.32, P < 0.000 01), National Institutes of Health Stroke Scale (NIHSS) score >10 (OR=3.35, 95%CI, 1.75 to 6.42, P=0.000 3), and gastric residual volume >150 mL (OR=7.13, 95%CI, 2.55 to 9.96, P=0.001).
Conclusion
This study provides a scientific basis for clinical healthcare professionals to early identify high-risk patients for aspiration, take targeted intervention measures, and prevent the occurrence of aspiration.
- neurocritical care patients,
- aspiration,
- influencing factors,
- Meta-analysis

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References (47)

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