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LIU Di, XU Tingting, LIU Shunying, LI Xiaojuan, MENG Nannan, LI Jing, ZHOU Haikang, WEI Wenping. Detection and analysis of allergens in children with allergic diseases in Yangzhou area[J]. Journal of Clinical Medicine in Practice, 2024, 28(21): 28-32. DOI: 10.7619/jcmp.20241280
Citation: LIU Di, XU Tingting, LIU Shunying, LI Xiaojuan, MENG Nannan, LI Jing, ZHOU Haikang, WEI Wenping. Detection and analysis of allergens in children with allergic diseases in Yangzhou area[J]. Journal of Clinical Medicine in Practice, 2024, 28(21): 28-32. DOI: 10.7619/jcmp.20241280
shu

Detection and analysis of allergens in children with allergic diseases in Yangzhou area

  • 1.

    Pediatrics Department, the Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu, 225000

  • 2.

    School of Medicine of Yangzhou University, Yangzhou, Jiangsu, 225000

  • 3.

    Pediatrics Department, Donghai County People's Hospital of Jiangsu Province, Lianyungang, Jiangsu, 222000

  • 4.

    Graduate School of Dalian Medical University, Dalian, Liaoning, 116000

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  • Received Date: March 26, 2024
  • Revised Date: August 10, 2024
    Graphical Abstract
    • Abstract
  • Objective 

    To analyze the distribution characteristics and clinical significance of allergens in children with allergic diseases in Yangzhou area.

    Methods 

    A total of 1, 025 children who were treated in the Affiliated Hospital of Yangzhou University from December 2022 to December 2023 and tested for allergens were selected as study objects. The detection results of allergens were collected and the distribution characteristics of allergens were analyzed.

    Results 

    Among the 1, 025 children with allergy-related diseases, 83.41% (855 cases) tested positive for allergens, with a positive rate of 66.24% (679 cases) for inhalant allergens and 61.17% (627 cases) for food allergens. The most common allergens were milk (36.20%), molds (33.27%), and house dust mites (30.34%). There was no statistically significant difference in the positive rate of allergens among different age groups (P>0.05). The positive rate of allergen detection in boys was higher than that in girls, the difference was statistically significant (P < 0.05). The positive rate of inhalation allergens in children with respiratory symptoms was higher than that of food allergens, and the positive rate of food allergens in children with digestive tract symptoms was higher than that of inhalation allergens (P < 0.05). For children with immune system diseases such as skin symptoms and allergic purpura, there was no statistically significant difference in the positive rates of inhalant and food allergens (P>0.05).

    Conclusion 

    The most common allergens in children with allergic diseases in Yangzhou area are milk, molds, and dust mites. Allergen testing can provide reference opinions for the prevention, diagnosis, and treatment of allergic diseases in children in Yangzhou area.

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    • References (20)
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