Rules of acupoints selection of acupuncture and moxibustion for treatment of epilepsy based on complex network and data mining

YU Yao; CHENG Guangyu; CHENG Weiping; WANG Jinyu; CONG Didi; DU Ruoqi

doi:10.7619/jcmp.20232906

Journal of Clinical Medicine in Practice > 2024 > 28(2): 43-48. > DOI: 10.7619/jcmp.20232906

YU Yao, CHENG Guangyu, CHENG Weiping, WANG Jinyu, CONG Didi, DU Ruoqi. Rules of acupoints selection of acupuncture and moxibustion for treatment of epilepsy based on complex network and data mining[J]. Journal of Clinical Medicine in Practice, 2024, 28(2): 43-48. DOI: 10.7619/jcmp.20232906

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Rules of acupoints selection of acupuncture and moxibustion for treatment of epilepsy based on complex network and data mining

1.
Graduate School of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, 150040
2.
Epolepsy Diagnosis and Treatment Center, the First Hospital Affiliated to Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, 150040
3.
the Second Department of Acupuncture and Moxibustion, the First Hospital Affiliated to Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, 150040

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Received Date: September 12, 2023
Revised Date: October 29, 2023
Available Online: January 25, 2024

Graphical Abstract

Abstract

Abstract

Objective
To explore the core acupoints and compatibility rules of acupuncture and moxibustion for epilepsy by using complex network method.
Methods
A prescription database was established through inclusion and exclusion criteria for searching literatures for databases from China National Knowledge Infrastructure, VIP, Wanfang, Web of Science, EMBASE, and Pubmed. SPSS Modeler software was used to analyze the frequency and correlation of acupoints, and Gephi0.10.1 software was used to establish a complex network model to explore the core acupoints and acupoint selection rules of prescriptions for epilepsy.
Results
Ultimately, 144 valid literatures were included, 199 prescriptions were extracted, involving 102 acupoints. Baihui acupoint had the highest frequency of use, specific acupoints were mainly Five-shu acupoint, the Eight Meridian Intersection acupoint, and the Back-shu acupoint. In selection of meridians, most acupoints were selected from governor meridian. Association rule analysis showed that Baihui-Taichong had the highest level of support and confidence. The analysis of complex network topology showed that 36 acupoints such as Baihui, Dazhui, Yaoqi and Fenglong were the core acupoints in the treatment of epilepsy by acupuncture and moxibustion. The analysis of acupoint communities revealed three major acupoint groups including governor meridian passing through treatment group, far and near matching acupoint group of the four limbs and head, and differentiation group of Zang-fu and body fluid for epilepsy treatment.
Conclusion
Acupoint compatibility of epilepsy by acupuncture and moxibustion should be mainly based on principle of the governor meridian combined with the differentiation of viscera and body fluid, and attention should be paid to distal-proximal point association.
- acupuncture and moxibustion,
- epilepsy,
- acupoint compatibility,
- complex networks,
- data mining

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