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WANG Zuohuan, WANG Lin, CAO Yang. Clinical application of mechanical power in evaluating ventilator-associated lung injury[J]. Journal of Clinical Medicine in Practice, 2023, 27(1): 131-134. DOI: 10.7619/jcmp.20222424
Citation: WANG Zuohuan, WANG Lin, CAO Yang. Clinical application of mechanical power in evaluating ventilator-associated lung injury[J]. Journal of Clinical Medicine in Practice, 2023, 27(1): 131-134. DOI: 10.7619/jcmp.20222424
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Clinical application of mechanical power in evaluating ventilator-associated lung injury

  • 1.

    College of Anesthesia of Guizhou Medical University, Guiyang, Guizhou, 550004

  • 2.

    Department of Anesthesiology, Guangzhou Red Cross Hospital of Guangdong Province, Guangzhou, Guangdong, 510220

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  • Received Date: August 07, 2022
  • Available Online: February 01, 2023
    Graphical Abstract
    • Abstract

  • With the pandemic of Coronavirus Disease 2019, the need for pulmonary mechanics assessment and ventilator-induced lung injury (VILI) monitoring tools has increased. Mechanical power (MP) as an emerging comprehensive parameter for VILI evaluation has received extensive clinical attention. In this paper, the definition and calculation formula of MP, the correlation between MP and VILI, and the related research progress of protective ventilation strategies induced by MP were reviewed in order to provide a new perspective for clinical avoidance of VILI.

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    • References (26)
  • [1]
    KATIRA B H. Ventilator-induced lung injury: classic and novel concepts[J]. Respir Care, 2019, 64(6): 629-637. doi: 10.4187/respcare.07055
    [2]
    CRESSONI M, GOTTI M, CHIURAZZI C, et al. Mechanical power and development of ventilator-induced lung injury[J]. Anesthesiology, 2016, 124(5): 1100-1108. doi: 10.1097/ALN.0000000000001056
    [3]
    MARINI J J, ROCCO P R M, GATTINONI L. Static and dynamic contributors to ventilator-induced lung injury in clinical practice. pressure, energy, and power[J]. Am J Respir Crit Care Med, 2020, 201(7): 767-774. doi: 10.1164/rccm.201908-1545CI
    [4]
    MARINI J J, GATTINONI L. Energetics and the root mechanical cause for ventilator-induced lung injury[J]. Anesthesiology, 2018, 128(6): 1062-1064. doi: 10.1097/ALN.0000000000002203
    [5]
    GATTINONI L, TONETTI T, CRESSONI M, et al. Ventilator-related causes of lung injury: the mechanical power[J]. Intensive Care Med, 2016, 42(10): 1567-1575. doi: 10.1007/s00134-016-4505-2
    [6]
    CABELLO B, MANCEBO J. Work of breathing[J]. Intensive Care Med, 2006, 32(9): 1311-1314. doi: 10.1007/s00134-006-0278-3
    [7]
    JUBRAN A, GRANT B J B, LAGHI F, et al. Weaning prediction: esophageal pressure monitoring complements readiness testing[J]. Am J Respir Crit Care Med, 2005, 171(11): 1252-1259. doi: 10.1164/rccm.200503-356OC
    [8]
    GIOSA L, BUSANA M, PASTICCI I, et al. Mechanical power at a glance: a simple surrogate for volume-controlled ventilation[J]. Intensive Care Med Exp, 2019, 7(1): 61. doi: 10.1186/s40635-019-0276-8
    [9]
    BECHER T, VAN DER STAAY M, SCHÖDLER D, et al. Calculation of mechanical power for pressure-controlled ventilation[J]. Intensive Care Med, 2019, 45(9): 1321-1323. doi: 10.1007/s00134-019-05636-8
    [10]
    VAN DER MEIJDEN S, MOLENAAR M, SOMHORST P, et al. Calculating mechanical power for pressure-controlled ventilation[J]. Intensive Care Med, 2019, 45(10): 1495-1497. doi: 10.1007/s00134-019-05698-8
    [11]
    GATTINONI L, MARINI J J, COLLINO F, et al. The future of mechanical ventilation: lessons from the present and the past[J]. Crit Care, 2017, 21(1): 183. doi: 10.1186/s13054-017-1750-x
    [12]
    MONJEZI M, JAMAATI H, NOORBAKHSH F. Attenuation of ventilator-induced lung injury through suppressing the pro-inflammatory signaling pathways: a review on preclinical studies[J]. Mol Immunol, 2021, 135: 127-136. doi: 10.1016/j.molimm.2021.04.007
    [13]
    XIE Y P, ZHENG H, MOU Z F, et al. High expression of CXCL10/CXCR3 in ventilator-induced lung injury caused by high mechanical power[J]. Biomed Res Int, 2022, 2022: 6803154.
    [14]
    DE PROST N, SAUMON G, DREYFUSS D. Modeling the time-course of ventilator-induced lung injury: what can we learn from inter species discrepancies?[J]. Intensive Care Med, 2011, 37(12): 1901-1903. doi: 10.1007/s00134-011-2394-y
    [15]
    COLLINO F, RAPETTI F, VASQUES F, et al. Positive end-expiratory pressure and mechanical power[J]. Anesthesiology, 2019, 130(1): 119-130. doi: 10.1097/ALN.0000000000002458
    [16]
    SANTER P, WACHTENDORF L J, SULEIMAN A, et al. Mechanical power during general anesthesia and postoperative respiratory failure: a multicenter retrospective cohort study[J]. Anesthesiology, 2022, 137(1): 41-54. doi: 10.1097/ALN.0000000000004256
    [17]
    URNER M, JVNI P, HANSEN B, et al. Time-varying intensity of mechanical ventilation and mortality in patients with acute respiratory failure: a registry-based, prospective cohort study[J]. Lancet Respir Med, 2020, 8(9): 905-913. doi: 10.1016/S2213-2600(20)30325-8
    [18]
    NETO A S, DELIBERATO R O, JOHNSON A E W, et al. Mechanical power of ventilation is associated with mortality in critically ill patients: an analysis of patients in two observational cohorts[J]. Intensive Care Med, 2018, 44(11): 1914-1922. doi: 10.1007/s00134-018-5375-6
    [19]
    SANTOS R S, MAIA L A, OLIVEIRA M V, et al. Biologic impact of mechanical power at high and low tidal volumes in experimental mild acute respiratory distress syndrome[J]. Anesthesiology, 2018, 128(6): 1193-1206. doi: 10.1097/ALN.0000000000002143
    [20]
    VASSALLI F, PASTICCI I, ROMITTI F, et al. Does Iso-mechanical power lead to Iso-lung damage: an experimental study in a porcine model[J]. Anesthesiology, 2020, 132(5): 1126-1137. doi: 10.1097/ALN.0000000000003189
    [21]
    ABBOTT T E F, FOWLER A J, PELOSI P, et al. A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications[J]. Br J Anaesth, 2018, 120(5): 1066-1079. doi: 10.1016/j.bja.2018.02.007
    [22]
    CHIUMELLO D, FORMENTI P, BOLGIAGHI L, et al. Body position alters mechanical power and respiratory mechanics during thoracic surgery[J]. Anesth Analg, 2020, 130(2): 391-401. doi: 10.1213/ANE.0000000000004192
    [23]
    SCHUIJT M T U, HOL L, NIJBROEK S G, et al. Associations of dynamic driving pressure and mechanical power with postoperative pulmonary complications-posthoc analysis of two randomised clinical trials in open abdominal surgery[J]. EClinicalMedicine, 2022, 47: 101397. doi: 10.1016/j.eclinm.2022.101397
    [24]
    UPADHYA S, REHMAN J, MALIK A B, et al. Mechanisms of lung injury induced by SARS-CoV-2 infection[J]. Physiology (Bethesda), 2022, 37(2): 88-100.
    [25]
    SENZI A, BINDI M, CAPPELLINI I, et al. COVID-19 and VILI: developing a mobile app for measurement of mechanical power at a glance[J]. Intensive Care Med Exp, 2021, 9(1): 6. doi: 10.1186/s40635-021-00372-0
    [26]
    GHIANI A, PADEREWSKA J, WALCHER S, et al. Mechanical power normalized to lung-Thorax compliance predicts prolonged ventilation weaning failure: a prospective study[J]. BMC Pulm Med, 2021, 21(1): 202. doi: 10.1186/s12890-021-01566-8
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