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WU Xiaomei, YU Junmin, ZHAO Yuanyuan, CHEN Hongye, LI Dahe, ZHANG Xiaobo. Research progress on coexistent mechanism of heart failure and atrial fibrillation in elderly patients[J]. Journal of Clinical Medicine in Practice, 2022, 26(24): 138-142. DOI: 10.7619/jcmp.20221892
Citation: WU Xiaomei, YU Junmin, ZHAO Yuanyuan, CHEN Hongye, LI Dahe, ZHANG Xiaobo. Research progress on coexistent mechanism of heart failure and atrial fibrillation in elderly patients[J]. Journal of Clinical Medicine in Practice, 2022, 26(24): 138-142. DOI: 10.7619/jcmp.20221892
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Research progress on coexistent mechanism of heart failure and atrial fibrillation in elderly patients

  • Department of Geriatrics, the Fourth Hospital Affiliated to Harbin Medical University, Harbin, Heilongjiang, 150001

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  • Received Date: June 16, 2022
  • Available Online: January 06, 2023
    Graphical Abstract
    • Abstract

  • Heart failure can induce atrial fibrillation by activating myocardial fibrosis, cardiac remodeling and renin-angiotension-aldosterone system (RAAS), and atrial electrical and structural remodeling can further aggravate heart failure. Inflammatory reaction, oxidative stress and neuroendocrine imbalance make the coexistent status of failure and atrial fibrillation, and also involve substance metabolism, non-coding ribonucleic acid (RNA) expression and immune regulation mechanism.

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