TONG Cong, WANG Weizhao, GU Da, ZHU Qinling, ZHAO Xiang'an, XIANG Xiaoxing. Analysis in clinical characteristics of type 2 diabetes mellitus complicated with liver abscess[J]. Journal of Clinical Medicine in Practice, 2021, 25(2): 54-58. DOI: 10.7619/jcmp.20200816
Citation: TONG Cong, WANG Weizhao, GU Da, ZHU Qinling, ZHAO Xiang'an, XIANG Xiaoxing. Analysis in clinical characteristics of type 2 diabetes mellitus complicated with liver abscess[J]. Journal of Clinical Medicine in Practice, 2021, 25(2): 54-58. DOI: 10.7619/jcmp.20200816

Analysis in clinical characteristics of type 2 diabetes mellitus complicated with liver abscess

More Information
  • Received Date: September 12, 2020
  • Available Online: January 26, 2021
  • Published Date: January 27, 2021
  •   Objective  To analyze the clinical characteristics of patients with diabetes and liver abscess.
      Methods  A total of 316 patients with liver abscess were selected as study objects, and were divided into diabetes mellitus group(n=144)and non-diabetes group(n=172) according to whether the patients suffered from type 2 diabetes or not. The general conditions, basic diseases, clinical symptoms and signs, laboratory examination results, imaging findings and etiological examination results of the two groups were analyzed.
      Results  The rates of patients with abdominal pain and abdominal distension, abdominal tenderness and rebound pain, and percussion pain in the liver area in the diabetic group were significantly lower than those in the non-diabetic group(P < 0.05). The levels of albumin, blood platelet and γ-glutamine transpeptidase in the diabetic group were significantly lower than those in the non-diabetic group (P < 0.05 or P < 0.01). The proportion of abscess diameter over 10 cm and incidence of sepsis in the diabetic group were significantly higher than those in the non-diabetic group (P < 0.05). The positive rates of Klebsiella pneumoniae in blood and pus culture in the diabetic group were significantly higher than those in the non-diabetic group (P < 0.05 or P < 0.01). Follow-up after treatment showed that the proportion of residual abscess with diameter of 5 to 10 cm in the diabetic group was significantly higher than that in the non-diabetic group (P < 0.05).
      Conclusion  Because of atypical clinical manifestations of diabetes mellitus complicated with liver abscess, misdiagnose and missed diagnosis may easily occur. Once diagnosed, sensitive antibiotics, blood sugar control and puncture treatment should be implemented so as to achieve better curative effect.
  • [1]
    DU Z Q, ZHOU X C, ZHAO J Z, et al. Effect of diabetes mellitus on short-term prognosis of 227 pyogenic liver abscess patients after hospitalization[J]. BMC Infect Dis, 2020, 20(1): 145. doi: 10.1186/s12879-020-4855-9
    [2]
    柴彦军, 李昇霖, 张国晋, 等. 侵袭性肺炎克雷伯菌肝脓肿综合征临床及影像学特点[J]. 中国医学影像技术, 2020, 36(8): 1202-1206. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXX202008027.htm
    [3]
    KIM E J, HA K H, KIM D J, et al. Diabetes and the risk of infection: a national cohort study[J]. Diabetes Metab J, 2019, 43(6): 804-814. doi: 10.4093/dmj.2019.0071
    [4]
    邵亚丽. 糖尿病合并肝脓肿的临床特征[J]. 肝脏, 2017, 22(2): 143-146. doi: 10.3969/j.issn.1008-1704.2017.02.016
    [5]
    张慧, 张照如, 李家斌. 细菌性肝脓肿合并糖尿病患者的临床特点[J]. 中华传染病杂志, 2017, 35(6): 364-368. doi: 10.3760/cma.j.issn.1000-6680.2017.06.009
    [6]
    何闽, 黄超玲, 王永钦, 等. 糖尿病合并肝脓肿临床诊疗分析[J]. 糖尿病新世界, 2017, 20(17): 21-22. https://www.cnki.com.cn/Article/CJFDTOTAL-TNBX201717011.htm
    [7]
    WANG W J, TAO Z, WU H L. Etiology and clinical manifestations of bacterial liver abscess: a study of 102 cases[J]. Medicine, 2018, 97(38): e12326. doi: 10.1097/MD.0000000000012326
    [8]
    LIU L, CHEN W, LU X, et al. Pyogenic liver abscess: a retrospective study of 105 cases in an emergency department from East China[J]. J Emerg Med, 2017, 52(4): 409-416. doi: 10.1016/j.jemermed.2016.09.026
    [9]
    LEE C R, LEE J H, PARK K S, et al. Antimicrobial resistance of hypervirulent Klebsiella pneumoniae: epidemiology, hypervirulence-associated determinants, and resistance mechanisms[J]. Front Cell Infect Microbiol, 2017, 7: 483. doi: 10.3389/fcimb.2017.00483
    [10]
    SHANKAR C, VEERARAGHAVAN B, NABARRO L E B, et al. Whole genome analysis of hypervirulent Klebsiella pneumoniae isolates from community and hospital acquired bloodstream infection[J]. BMC Microbiol, 2018, 18(1): 6. doi: 10.1186/s12866-017-1148-6
    [11]
    JUN J B. Klebsiella pneumoniae liver abscess[J]. Infect Chemother, 2018, 50(3): 210-218. doi: 10.3947/ic.2018.50.3.210
    [12]
    王金华, 潘建新, 杨为霞. 2型糖尿病并发细菌性肝脓肿患者的临床特点与生存状况[J]. 实用临床医药杂志, 2019, 23(3): 82-84, 92. doi: 10.7619/jcmp.201903022
    [13]
    毕旭东, 赵晶, 王海龙, 等. 糖尿病并发细菌性肝脓肿的治疗[J]. 中国现代医学杂志, 2006, 16(17): 2694-2695, 2697. doi: 10.3969/j.issn.1005-8982.2006.17.044
  • Related Articles

    [1]YANG Shuangyue, JIN Xing, MENG Zhaoxiang, KE Minghui, ZHANG Minjie, CHEN Chen. Efficacy of low-frequency repetitive transcranial magnetic stimulation assisted virtual reality interactive robot training on function of upper limbs in patients with stroke[J]. Journal of Clinical Medicine in Practice, 2025, 29(1): 28-32. DOI: 10.7619/jcmp.20243115
    [2]WU Yusi, JIANG Mingqing, LUO Hua, RUAN Jianghai. Research on spontaneous upper limb activity and graph theory of electroencephalogram in patients with acute ischemic stroke[J]. Journal of Clinical Medicine in Practice, 2024, 28(19): 73-78. DOI: 10.7619/jcmp.20242749
    [3]ZHAO Huiduo, WU Bing, CHE Zhiying. Construction and validation of risk predictive visualized model of upper limb lymphedema after breast cancer surgery[J]. Journal of Clinical Medicine in Practice, 2023, 27(24): 30-36. DOI: 10.7619/jcmp.20232484
    [4]ZHAO Chunhong, FENG Xuguang, WANG Xiaoxi, YIN Changheng. Effect of upper limb rehabilitation training combined with microwave hyperthermia for breast cancer patients undergoing peripherally inserted central catheter[J]. Journal of Clinical Medicine in Practice, 2021, 25(8): 39-42. DOI: 10.7619/jcmp.20210016
    [5]SONG Lin. Effect of group psychological intervention on psychological disturbance and upper extremity exercise in patients with breast cancer undergoing radical mastectomy[J]. Journal of Clinical Medicine in Practice, 2020, 24(11): 121-124. DOI: 10.7619/jcmp.202011033
    [6]HU Jie. Study on functional recovery and rehabilitation nursing in patients with breast cancer after radical operation[J]. Journal of Clinical Medicine in Practice, 2019, 23(24): 111-113, 117. DOI: 10.7619/jcmp.201924035
    [7]WANG Hailin. Effect of stage nursing intervention on function recovery of affected upper limbs in postoperative patients with breast cancer[J]. Journal of Clinical Medicine in Practice, 2018, (6): 90-92. DOI: 10.7619/jcmp.201806026
    [8]WANG Weifeng, CHEN Shi, SUN Qiong, WANG Shiqun. Effect of doctor-nurse integration health education on prevention of upper limb edema after breast cancer surgery[J]. Journal of Clinical Medicine in Practice, 2017, (12): 73-76. DOI: 10.7619/jcmp.201712022
    [9]ZHAO Shuai, HOU Nina. Effect of evidence-based nursing on upper limb function in breast cancer patients with postoperative radiotherapy[J]. Journal of Clinical Medicine in Practice, 2015, (18): 45-47,51. DOI: 10.7619/jcmp.201518015
    [10]ZHENG Li, JIANG Yinfen, CAI Lichun, LIU Hong, CHEN Bo. Research on postoperative early functional exercise in patients with mastoscope-assisted breast cancer surgery[J]. Journal of Clinical Medicine in Practice, 2013, (18): 4-6. DOI: 10.7619/jcmp.201318002

Catalog

    Article views (450) PDF downloads (40) Cited by()

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return