Advance Search
ZHANG Wenjing, YU Yanfang, WEI Wei, TU Chunlin. Effect of two oxygen therapy methods in treatment of patients with acute exacerbation of chronic obstructive pulmonary disease combined with type Ⅱ respiratory failure[J]. Journal of Clinical Medicine in Practice, 2021, 25(1): 50-53. DOI: 10.7619/jcmp.20200672
Citation: ZHANG Wenjing, YU Yanfang, WEI Wei, TU Chunlin. Effect of two oxygen therapy methods in treatment of patients with acute exacerbation of chronic obstructive pulmonary disease combined with type Ⅱ respiratory failure[J]. Journal of Clinical Medicine in Practice, 2021, 25(1): 50-53. DOI: 10.7619/jcmp.20200672
shu

Effect of two oxygen therapy methods in treatment of patients with acute exacerbation of chronic obstructive pulmonary disease combined with type Ⅱ respiratory failure

  • Department of Respiratory Medicine, Jiading District Central Hospital Affiliated to Shanghai Health Medical College, Shanghai, 201800

More Information
  • Received Date: March 20, 2020
  • Available Online: January 17, 2021
  • Published Date: January 14, 2021
    Graphical Abstract
    • Abstract
  •   Objective  To investigate the clinical efficacy of high-flow nasal canula (HFNC) and conventional nasal catheter oxygen therapy in patients with acute exacerbation of chronic obstructive pulmonary disease combined with type Ⅱ respiratory failure.
      Methods  Seventy-five patients with AECOPD combined with type Ⅱ respiratory failure were divided into the control group (n=36) and the experimental group (n=39). The control group was given conventional nasal catheter oxygen therapy on the basis of conventional treatment, while the experimental group was given HFNC on the basis of conventional treatment. The changes of arterial oxygen partial pressure [pa(O2)], arterial carbon dioxide partial pressure [pa(CO2)], oxygen saturation (SpO2), respiratory frequency, heart rate, forced expiratory volume in one second (FEV1), forced vital capacity (FVC), sputum viscosity, and sputum volume were compared in the two groups.
      Results  After treatment, the improvement of pa(CO2), respiration rate, heart rate, sputum viscosity and sputum volume in the experimental group showed significant difference compared with those in the control group (P< 0.05).
      Conclusion  HFNC is superior to traditional nasal catheter oxygen therapy in the treatment of patients with AECOPD combined with type Ⅱ respiratory failure, which can effectively improve the ventilation efficiency, decrease the respiratory rate, and reduce the repeated inhalation of carbon dioxide.
    • FullText(HTML)
    • References (17)
  • [1]
    黄慧, 徐作军. 肺动脉内径增宽与慢性阻塞性肺疾病急性加重期的关系[J]. 中华结核和呼吸杂志, 2012, 35(12): 945-945.
    [2]
    RAM F S F, PICOT J, LIGHTOWLER J, et al. Non-invasive positive pressure ventilation for treatment of respiratory failure due to exacerbations of chronic obstructive pulmonary disease[J]. Cochrance Database Syst Rev, 2004: CD004104. http://en.cnki.com.cn/Article_en/CJFDTOTAL-DSDX200408031.htm
    [3]
    BOURBEAU J, GAGNON S, ROSS B. Chronic obstructive pulmonary disease[J]. Canadian Journal of Respiratory, Critical Care, and Sleep Medicine, 2020, 4(sup1): S28-S33. doi: 10.1080/24745332.2020.1716650
    [4]
    苏科文, 陈静. HFNC治疗在COPD合并呼吸衰竭患者中的应用[J]. 北华大学学报(自然), 2019, 20(02): 94-97. https://www.cnki.com.cn/Article/CJFDTOTAL-ZLYY201902019.htm
    [5]
    STORGAARD L H, WEINREICH U M, LAURSEN B S. COPD Patients′ Experience of Long-Term Domestic Oxygen-Enriched Nasal High Flow Treatment: A Qualitative Study[J]. COPD Journal of Chronic Obstructive Pulmonary Disease, 2020, 17(8222): 1-9. doi: 10.1080/15412555.2020.1736998
    [6]
    陈颖, 万久贺, 王红, 等. 无创通气与经鼻高流量氧疗治疗COPD合并Ⅱ型呼吸衰竭的临床疗效[J]. 国际呼吸杂志, 2020, 40(20): 1570-1575. doi: 10.3760/cma.j.cn131368-20200414-00296
    [7]
    中华医学会呼吸病学分会慢性阻塞性肺疾病学组. 慢性阻塞性肺疾病诊治指南(2013年修订版)[J]. 中华结核和呼吸杂志, 2013, 36(4): 255-264. doi: 10.3760/cma.j.issn.1001-0939.2013.04.007
    [8]
    郭瑾, 关巍. 氧疗在慢性阻塞性肺疾病中应用的研究进展[J]. 山东医药, 2020, 060(008): 109-112. https://www.cnki.com.cn/Article/CJFDTOTAL-SDYY202008030.htm
    [9]
    RESTREPO R D, WALSH B K. Humidification during invasive and noninvasive mechanical ventilation[J]. Respir Care, 2012, 57(5): 782-788. doi: 10.4187/respcare.01766
    [10]
    CHANQUES G, CONSTANTIN J M, SAUTER M, et al. Discomfort associated with under humidified high-flow oxygen therapy in critically ill patients[J]. Intensive Care Med, 2009, 35(6): 996-1003. doi: 10.1007/s00134-009-1456-x
    [11]
    ROSA D M, SAVINO S, TANIA S, et al. High-flow nasal cannula oxygen therapy decreases postextubation neuroventilatory drive and work of breathing in patients with chronic obstructive pulmonary disease[J]. Critical Care, 2018, 22(1): 180-182. doi: 10.1186/s13054-018-2107-9
    [12]
    GROVES N, TOBIN A. High flow nasal oxygen generates positive airway pressure in adult volunteers[J]. Aust Crit care, 2007, 20(4): 126-131. doi: 10.1016/j.aucc.2007.08.001
    [13]
    MÖLLER W, FENG S, DOMANSKI U, et al. Nasal high flow reduces dead space[J]. J Appl physiol, 2017, 122(1): 191-197. doi: 10.1152/japplphysiol.00584.2016
    [14]
    PILCHER J, EASTLAKE L, RICHARDS M, et al. Physiological effect of titrated oxygen via nasal high-flow cannulae in copd exacerbations: A randomized controlled cross-over trial[J]. Respirology, 2017, 22(6): 1149-1155. doi: 10.1111/resp.13050
    [15]
    FRASER J F, SPOONER A J, DUNSTER K R, et al. Nasal high flow oxygen therapy in patients with COPD reduces respiratory rate and tissue carbon dioxide while increasing tidal and end-expiratory lung volumes: a randomised crossover trial[J]. Thorax, 2016, 71(8): 759-761. doi: 10.1136/thoraxjnl-2015-207962
    [16]
    NILIUS G, FRANKE K J, DOMANSKI U, et al. Effects of Nasal Insufflation on Arterial Gas Exchange and Breathing Pattern in Patients with Chronic Obstructive Pulmonary Disease and Hypercapnic Respiratory Failure[J]. Adv Exp Med Biol, 2013, 755: 27-34. doi: 10.1007/978-94-007-4546-9_4
    [17]
    DYSART K, MILLER T L, WOLFSON M R, et al. Research in high flow therapy: mechanisms of action[J]. Resp Med, 2009, 103(10): 1400-1405. doi: 10.1016/j.rmed.2009.04.007
    • Related Articles

  • Cited by

    Periodical cited type(2)

    1. 张锦贤. 超早期钛网手术对神经功能的影响研究. 浙江创伤外科. 2024(03): 529-531 .
    2. 游嘉，张青青，程康杰，徐略乾，姜献峰，MSHAl-Furjan，刘云峰. 聚醚酮酮材料个性化人工颅骨植入体热压成型工艺仿真及实验. 高技术通讯. 2024(12): 1297-1306 .

    Other cited types(0)

Catalog

    Get Citation
    PDF
    XML
    Article views (281) PDF downloads (19) Cited by(2)
    Turn off MathJax
    Article Contents
    Abstract
    References

    © 2020 《实用临床医药杂志》编辑部

    Address: 江苏省扬州市江阳中路136号，扬州大学江阳路北校区14号楼201室China Pos: 225009Tel: 0514-87978917、87978989、87978807

    苏公网安备 32100302010246号

    Supported by: Beijing Renhe Information Technology Co., Ltd.   Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return