Value of CT vascular signs of lung ground-glass nodule in differential diagnosis of pathologic subtypes of lung adenocarcinoma

MEI Xia; WANG Litong

doi:10.7619/jcmp.202003007

Journal of Clinical Medicine in Practice > 2020 > 24(3): 22-25. > DOI: 10.7619/jcmp.202003007

MEI Xia, WANG Litong. Value of CT vascular signs of lung ground-glass nodule in differential diagnosis of pathologic subtypes of lung adenocarcinoma[J]. Journal of Clinical Medicine in Practice, 2020, 24(3): 22-25. DOI: 10.7619/jcmp.202003007

Citation:

PDF (522 KB)

Value of CT vascular signs of lung ground-glass nodule in differential diagnosis of pathologic subtypes of lung adenocarcinoma

MEI Xia¹,
WANG Litong^2, ,

1. Department of Radiology, Yangzhou Maternal and Child Health Care Hospital, The Affiliated Hospital of Medical College of Yangzhou University, Yangzhou, Jiangsu, 225001;
2. The Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu, 225001

More Information

Received Date: November 10, 2019

Graphical Abstract

Abstract

Abstract

Objective To analyze the relationship and typing between ground-glass nodule(GGN)and peripheral blood vessels, and to explore its value in differential diagnosis of pathological classification of lung adenocarcinoma. Methods The clinical data of 92 patients with GGN(100 GGN)were analyzed retrospectively. They were divided into three groups, that were pre-invasion lesion group(n=48), microinvasive adenocarcinoma(MIA)group(n=30)and invasive adenocarcinoma(IAC)group(n=22). According to the relationship between GGN and peripheral blood, it can be divided into four types, that were type Ⅰ, type Ⅱ, type Ⅲ and type Ⅳ. Results In this study, the size of GGN was(7.99±3.18)mm in the pre-invasion lesion group,(8.75±2.87)mm in the MIA group and(13.47±4.48)mm in the IAC group. There were significant differences in GGN size between IAC group and pre-invasion lesion group as well as MIA group(P < 0.05). There were significant differences in peripheral vascular signs between every two groups(P < 0.01). The relationship between GGN with different proportion of ground glass components and vascular classification revealed that there were significant differences in typing of peripheral vascular signs between class A and class B, class A and class C, and class B and class C(P < 0.01). Conclusion The peripheral vascular- sign of GGN play an important role in the differential diagnosis of lung adenocarcinoma, and the accuracyof differential diagnosis can be further improved by combining the size of GGN and the proportion of ground-glass opacity contained in GGN.
- ground-glass nodules,
- vascular signs,
- lung adenocarcinoma,
- differential diagnosis

FullText(HTML)

References (17)

References

Nakamura S, Fukui T, Taniguchi T, et al. Prognostic impact of tumor size eliminating the ground glass opacity component[J]. J Thorac Oncol, 2013, 8(12): 1551-1557.

Lee G D, Park C H, Park H S, et al. Lung adenocarcinoma invasiveness risk in pure ground-glass opacity lung nodules smaller than 2 cm[J]. Thorac cardiovasc Surg, 2018, 22(18): 189-195.

Travis W D, Brambilla E, Noguchi M, et al. International association for the study of lung cancer/American Thoracic Society/European Respiratory Society: international multidisciplinary classification of lung adenocarcinoma[J]. J Thorac Oncol, 2011, 6(2): 244-285.

刘念龙, 杨波, 王玉璜, 等. 肺微小磨玻璃结节血管征及气管征对良恶性的鉴别意义[J]. 中国肿瘤外科杂志, 2018, 10(4): 221-224.

Gao F, Li M, Ge X, et al. Multi-detector spiral CT study of the relationships between pulmonary ground-glass nodules and blood vessels[J]. Eur Radiol, 2013, 23(12): 3271-3277.

Aoki T, Tomoda Y, Watanabe H, et al. Peripheral lung adenocarcinoma: correlation of thin-section CT findings with histologic prognostic factors and survival [J]. Radiology, 2001, 220(3): 803-809.

刘晨鹭, 蔡庆, 沈玉英, 等. 微小磨玻璃结节样肺腺癌的HRCT血管征研究[J]. 实用放射学杂志, 2018, 34(1): 31-34

, 50.

Naidich D P, Bankier A A, MacMahon H, et al. Recommendations for the management of subsolid pulmonary nodules detected at CT: a statement from the Fleischner Society[J]. Radiology, 2013, 266(1): 304-317.

Lee S M, Park C M, Goo J M, et al. Invasive pulmonary adenocarcinomas versus preinvasive lesions appearing as ground-glass nodules: differentiation by using CT features[J]. Radiology, 2013, 268(1): 265-273.

Liu LH, Liu M, Wei R, et al. CT findings of persistent pure ground glass opacity: can we predict the invasiveness[J] APJCP, 2015, 16(5): 1925-1928.

李西, 肖湘生, 于红, 等. 大于5 mm肺部纯磨玻璃结节的MDCT表现与病理对照研究[J]. 实用放射学杂志, 2016, 32(7): 1023-1027.

Lee H Y, Choi Y L, Lee K S, et al. Pure ground-glass opacity neoplastic lung nodules: histopathology, imaging, and management[J]. AJR, 2014, 202(3): 224-233.

陈群慧, 叶晓丹, 朱莉, 等. 肺孤立性磨玻璃密度结节的超高分辨力CT表现及与病理的相关性[J]. 放射学实践, 2014, 29(1): 57-60.

王群, 俞炳根, 王文森, 等. MSCT对肺部局灶性磨玻璃结节的诊断价值[J]. 实用放射学杂志, 2016, 32(3): 362-365.

Liang J, Xu X Q, Xu H, et al. Using the CT features to differentiate invasive pulmonary adenocarcinoma from pre-invasive lesion appearing as pure or mixed ground-glass nodules[J]. Br J of Radiol, 2015, 88(1053): 20140811-20140819.

李铭, 高丰, 郑向鹏, 等. 肺内亚厘米磨玻璃结节的CT诊断与鉴别[J]. 实用放射学杂志, 2014, 30(3): 416-420.

高丰, 葛虓俊, 李铭, 等. 不同病理类型肺部磨玻璃结节的CT诊断[J]. 中华肿瘤杂志, 2014, 36(3): 188-192.

Cited By

Cited by

Periodical cited type(14)

1.	张华朋，章赛玉，陈华永. 七氟烷对冠心病颅脑手术患者行控制性降血压的脑保护效果. 中国当代医药. 2021(09): 117-120 .
2.	杜力侠，沈如刚. 静吸复合麻醉与全凭静脉麻醉在急性创伤性颅脑损伤患者治疗中的效果分析. 系统医学. 2021(19): 4-7 .
3.	张娇娇，薛志强，刘丽霞. 异丙酚联合地氟烷麻醉对颅脑损伤患者的脑保护作用研究. 湖南师范大学学报(医学版). 2020(01): 142-145 .
4.	郝维强，魏宏姗. 重型颅脑损伤丙泊酚麻醉临床分析. 中国继续医学教育. 2020(06): 70-73 .
5.	汪金娇，李海中，刘彦锋. 丙泊酚全身麻醉对颅脑外伤急诊手术患者神经损伤程度及氧化应激影响. 社区医学杂志. 2020(11): 792-795 .
6.	张志伟，孙荣青. 右美托咪定联合瑞芬太尼在重型颅脑损伤术后镇痛镇静效果. 内蒙古医学杂志. 2020(08): 959-960 .
7.	李军根，陆士奇，肖接承，丁礼. 全凭静脉麻醉与静吸复合麻醉对重症颅脑创伤患者血流动力学及IL-6、ADR、NADR水平的影响. 现代医学与健康研究电子杂志. 2020(15): 72-74 .
8.	王安平，岳新霞，海力茜·陶尔大洪，陈新，罗庆元. 丙泊酚对重型颅脑损伤手术患者血流动力学、术后镇痛镇静效果及血清hs-CRP、PCT、IL-22表达的影响. 解放军医药杂志. 2019(02): 107-112 .
9.	潘明，贾衍杰. 丙泊酚静脉麻醉在急性重型颅脑损伤手术患者中的应用效果. 中国当代医药. 2019(02): 183-185 .
10.	王仕斌，王雪婷，薛荣亮，陈蓉，路丕周，刘世明. 异丙酚联合地氟烷麻醉对颅脑损伤患者脑保护及脑供氧平衡的影响. 现代生物医学进展. 2019(24): 4793-4796 .
11.	陈艳霞. 瑞芬太尼复合丙泊酚对重型颅脑损伤患者脑氧代谢及炎症因子的影响. 临床研究. 2018(11): 36-38 .
12.	吴悠扬，周春丽，王勇. 丙泊酚复合瑞芬太尼靶控输注联合灯盏细辛注射液对脑胶质瘤切除术患者脑保护及苏醒质量的影响. 现代中西医结合杂志. 2018(29): 3290-3293 .
13.	田佩松. 颅脑损伤手术中全凭静脉麻醉与静吸复合麻醉的应用效果对比. 实用医技杂志. 2018(12): 1385-1387 .
14.	许镇. 右美托咪定与丙泊酚对重症颅脑损伤患者脑代谢及预后的影响比较. 中外医学研究. 2018(31): 148-149 .

Other cited types(0)

Get Citation

PDF

XML

Article views (535) PDF downloads (9) Cited by(14)

Turn off MathJax

Article Contents

Abstract

References

Value of CT vascular signs of lung ground-glass nodule in differential diagnosis of pathologic subtypes of lung adenocarcinoma

Abstract

References

Cited by

Periodical cited type(14)

Other cited types(0)

Catalog

Export File

Citation

Format

Content