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BAI Yu, YANG Yaming. Application of azithromycin combined with simvastatin in treating patients with chronic obstructive pulmonary disease complicated with pulmonary hypertension[J]. Journal of Clinical Medicine in Practice, 2019, 23(10): 33-35. DOI: 10.7619/jcmp.201910010
Citation: BAI Yu, YANG Yaming. Application of azithromycin combined with simvastatin in treating patients with chronic obstructive pulmonary disease complicated with pulmonary hypertension[J]. Journal of Clinical Medicine in Practice, 2019, 23(10): 33-35. DOI: 10.7619/jcmp.201910010
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Application of azithromycin combined with simvastatin in treating patients with chronic obstructive pulmonary disease complicated with pulmonary hypertension

  • 1.

    Department of Respiratory Medicine, Baota District People′s Hospital in Yan′an City, Yan′an, Shaanxi, 716000

  • 2.

    Department of Respiratory Medicine, Second Hospital of Traditional Chinese Medicine, Baoji, Shaanxi, 721300

More Information
  • Received Date: February 09, 2019
  • Accepted Date: April 16, 2019
  • Available Online: February 22, 2021
  • Published Date: May 27, 2019
    Graphical Abstract
    • Abstract
  •   Objective  To investigate the value of azithromycin combined with simvastatin in patients with chronic obstructive pulmonary disease (COPD) complicated with pulmonary hypertension.
      Methods  Eighty COPD patients with pulmonary hypertension were enrolled in our hospital. The control group with 40 patients were treated with simvastatin alone, and 40 patients in the observation group were treated with azithromycin combined with simvastatin. The treatment effects of the two groups were compared.
      Results  After different treatments, the differences in blood oxygen partial pressure, blood oxygen saturation, 6-min walking distance, lung function indexes and pulmonary artery pressure levels were statistically significant (P < 0.05). After treatment, the level of C-reactive protein in the observation group was significantly lower than that in the control group (P < 0.05).
      Conclusion  Azithromycin combined with simvastatin is of great significance in improving the disease condition of patients with COPD complicated with pulmonary hypertension.
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    • References (18)
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