三阴性乳腺癌82例临床特征与预后分析

张晓兰, 王水, 郑琳

张晓兰, 王水, 郑琳. 三阴性乳腺癌82例临床特征与预后分析[J]. 实用临床医药杂志, 2012, (15): 142-144.
引用本文: 张晓兰, 王水, 郑琳. 三阴性乳腺癌82例临床特征与预后分析[J]. 实用临床医药杂志, 2012, (15): 142-144.
ZHANG Xiao-lan, WANG Shui, ZHENG Lin. Clinical analysis and prognosis of triple-negative breast cancer in 82 patients[J]. Journal of Clinical Medicine in Practice, 2012, (15): 142-144.
Citation: ZHANG Xiao-lan, WANG Shui, ZHENG Lin. Clinical analysis and prognosis of triple-negative breast cancer in 82 patients[J]. Journal of Clinical Medicine in Practice, 2012, (15): 142-144.

三阴性乳腺癌82例临床特征与预后分析

详细信息
  • 中图分类号: R737.9

Clinical analysis and prognosis of triple-negative breast cancer in 82 patients

  • 摘要: 目的 分析三阴性乳腺癌的临床、病理特征及预后情况.方法 回顾分析2008年1月~2011年12月本院收治的82例三阴性乳腺癌患者的发病率、肿瘤大小、病理资料、治疗及预后情况.结果 82例三阴性乳腺癌均通过术后病理确诊,占同期乳腺癌患者总数的17%.患者肿瘤直径0.5~15 cm.其中腋窝淋巴结转移27例(32.9%).结论 三阴性乳腺癌是发病率低、组织学分级高、复发转移快、死亡率高、治疗手段有限的高度恶性肿瘤.术前行新辅助化疗可能对延缓复发有益.
  • Kaplan H G, Malmgren J A, Atwood M K. Impact of triple negative phenotype on breast cancer prognosis [A]. 2006.14.
    Anders C K, Carey L A. Biology, metastatic patterns, and treatment of patients with triple-negative breast cancer [J]. Clinical Breast Cancer, 2009, (suppl 2):S73.
    Garcia M, Jemal A, Ward E M. Global Cancer Facts & Figures, 2007 [M]. Atlanta, GA:American Cancer Society, 2007.
    Carey L A, Perou C M, Livasy C A. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study [J]. Journal of the American Medical Association, 2006, (21):2492.
    Dent R, Trudeau M, Pritchard K J. Triple negative breast cancer:features and patterns of recurrence [J]. Clinical Cancer Research, 2007, (15):4429.
    Rakha E A, EI-Sayed ME, Green AR. Prognostic markers in triple negative breast cancer [J]. Cancer, 2007(1):25.
    Umemura S, Takekoshi S, Suzuki Y. Estrogen receptornegative and human epidermal growth factor receptor 2-negative breast cancer tissue have the highest Ki-67 labeling index and EGFR expression:gene amplification does not contribute to EGFR expression [J]. Oncology Reports, 2005(2):337.
    杨德宏, 刘红, 赵晶. 三阴型乳腺癌临床病理特征及预后分析 [J]. 中国肿瘤临床, 2008(9):501.doi: 10.3969/j.issn.1000-8179.2008.09.008.
    袁中玉, 壬树森, 高岩. 305例三阴乳腺癌患者的临床特征及预后因素分析 [J]. 癌症, 2008(6):561.doi: 10.3321/j.issn:1000-467X.2008.06.001.
    Liu Z B, Liu G Y, Yang WT. Triple-negative breast cancer types exhibit a distinct poor clinical characteristic in lymph node-negative Chinese patients [J]. Oncology Reports, 2008(4):987.
    Bauer K R, Brown M, Cress R D. Descriptive analysis of estrogen receptor (ER)-negative progesterone receptor (PR)-negative and HER2-negative invasive breast cancer, the so-called triple-negative phenotype:a population based study from the California cancer Registry [J]. Cancer, 2007.1721.
    Liedtke C, Mazouni C, Hess K R. Response to Neoadjurant Therapy and long-term survival in patients with triple-negative brest cancer [J]. Journal of Clinical Oncology, 2008(8):1275.
    Livasy C A, Karaca G, Nanda R. Phenotypic cevaluation of the basal-like subtype to invasive breast carcinoma [J]. Modern Pathology, 2006.264.
    祝玉祥, 章佳新, 邵稳喜. ki67在三阴性乳腺癌组织中的表达及意义 [J]. 中国现代普通外科进展, 2010(9):679.doi: 10.3969/j.issn.1009-9905.2010.09.003.
    Simhi B, Amedos M, Popat S. Platinum-based chemotherapy in triple-negative breast cancer [J]. Amm Oncol, 2008, (11):1847.
    Miller K, Wang M, Gralow J. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer [J]. New England Journal of Medicine, 2007, (26):2666.
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出版历程
  • 发布日期:  2012-12-19

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