Abstract: This article summarizes the rapid rehabilitation nursing experience for one pediatric patient with pancreatic divisum who underwent en bloc pancreatoduodenectomy preserving the duodenum, common bile duct, and Oddi's sphincter (DCOPPHTR). The nursing care encompassed preoperative prehabilitation to enhance physical and psychological preparation, postoperative precise volume and dynamic blood glucose management, early mobilization to facilitate recovery, personalized nutritional support to improve nutritional status, psychological nursing to bolster confidence, and family involvement to enhance quality of life. The pediatric patient experienced rapid recovery and was discharged from the hospital. A six-month follow-up indicated a significant improvement in quality of life.