高级检索

脐静脉导管彩色多普勒超声血流频谱参数及心肌做功指数诊断胎儿心脏畸形的价值

Value of umbilical vein catheter color Doppler ultrasonic blood flow spectral parameters and myocardial performance index in diagnosing fetal heart malformation

    摘要
  • 摘要:
    目的 探讨产前超声指标诊断妊娠期胎儿心脏畸形的价值。
    方法 采用病例-对照研究方法，选取本院随访证实的76例心脏畸形胎儿作为病例组，另选取76例无任何心脏畸形的胎儿作为对照组。比较2组孕期超声检查结果，包括脐静脉导管彩色多普勒超声血流频谱参数、心轴角度、心肌做功指数(MPI)。采用受试者工作特征(ROC)曲线分析各项指标在孕期辅助诊断胎儿心脏先天畸形中的价值。
    结果 病例组心室收缩速度、心房收缩期峰值速度、心室舒张期峰值速度、A波最大速度均低于对照组，搏动指数、静脉前负荷指数、静脉峰值血流指数均高于对照组，差异有统计学意义(P < 0.05)。心室收缩速度、心室舒张期峰值速度、心房收缩期峰值速度、A波最大速度、搏动指数、静脉前负荷指数、静脉峰值血流指数诊断胎儿心脏畸形的ROC曲线的曲线下面积(AUC)依次为0.680、0.753、0.590、0.859、0.674、0.715、0.663。病例组左心室MPI、右心室MPI、心轴角度均高于对照组，差异有统计学意义(P < 0.05)。左心室MPI、右心室MPI、心轴角度诊断胎儿心脏畸形的ROC曲线的AUC依次为0.502、0.571、0.712。
    结论 孕期实施脐静脉导管彩色多普勒超声血流频谱参数、心轴角度、MPI筛查，对于辅助诊断胎儿心脏畸形具有重要的参考价值。

     

    Abstract:
    Objective To explore the value of prenatal ultrasound indicators in diagnosing fetal heart malformation during pregnancy.
    Methods A case-control study was conducted, and 76 fetuses with confirmed heart malformation during follow-up in the hospital were selected as case group, and another 76 fetuses without any heart malformation were selected as control group. The results of ultrasound examinations during pregnancy for both groups were compared, including umbilical vein catheter color Doppler ultrasonic blood flow spectral parameters, cardiac axis angle, and myocardial performance index (MPI). Receiver operating characteristic (ROC) curve was used to analyze the value of each indicator in auxiliary diagnosis of fetal congenital heart malformation during pregnancy.
    Results The ventricular systolic velocity, peak atrial systolic velocity, peak ventricular diastolic velocity, and maximum A-wave velocity in the case group were significantly lower than those in the control group, while the pulsatility index, venous preload index, and venous peak flow index were significantly higher than those in the control group (P < 0.05). Values of area under the curve (AUC) of ROC curves for ventricular systolic velocity, peak ventricular diastolic velocity, peak atrial systolic velocity, maximum A-wave velocity, pulsatility index, venous preload index, and venous peak flow index in diagnosing fetal heart malformation were 0.680, 0.753, 0.590, 0.859, 0.674, 0.715 and 0.663, respectively. The left ventricular MPI, right ventricular MPI, and cardiac axis angle in the case group were significantly higher than those in the control group (P < 0.05). The values of AUC for left ventricular MPI, right ventricular MPI, and cardiac axis angle in diagnosing fetal heart malformation were 0.502, 0.571 and 0.712, respectively.
    Conclusion Implementation of umbilical vein catheter color Doppler ultrasonic blood flow spectral parameters, cardiac axis angle, and MPI screening during pregnancy has important reference value for auxiliary diagnosis of fetal heart malformation.

     

    • HTML全文
    • 参考文献(20)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回