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神经重症患者误吸影响因素的Meta分析

Influencing factors of aspiration in neurological critically ill patients: a Meta-analysis

    摘要
  • 摘要:
    目的 通过Meta分析评价神经重症患者发生误吸的影响因素。
    方法 检索PubMed、Embase、Web of Science、中国知网和万方数据库中自建库至2023年10月1日的文献, 获取神经重症患者误吸影响因素的相关文献。由2名研究者进行文献筛选、资料提取和文献质量评价。采用RevMan5.4软件进行Meta分析，并运用Stata13.0软件进行发表偏倚检验。
    结果 本研究共纳入8篇文献，包括1 315例神经重症患者，共提取9个误吸相关影响因素进行Meta分析。Meta分析结果显示，引起神经重症患者误吸的3个影响因素分别为卒中史(OR=5.03, 95%CI: 2.71~9.32, P < 0.000 01)、美国国立卫生研究院卒中量表(NIHSS)评分>10分(OR=3.35, 95%CI: 1.75~6.42, P=0.000 3)和胃残余量>150 mL(OR=7.13, 95%CI: 2.55~9.96, P=0.001)。
    结论 本研究为临床医护人员早期识别误吸高危患者、采取针对性干预措施和防范误吸发生提供了科学依据。

     

    Abstract:
    Objective To evaluate the influencing factors of aspiration in neurological critically ill patients by Meta-analysis.
    Methods PubMed, Embase, Web of Science, CNKI, and Wanfang Data were searched from inception to 1 October, 2023, to obtain relevant studies on influencing factors of aspiration in neurological critically ill patients. The literature screening, data extraction and quality evaluation were completed by two researchers. RevMan 5.4 and Stata 13.0 software were applied for pooled Meta-analysisand assessed publication bias, respectively.
    Results A total of 8 articles, including 1, 315 neurocritical care patients, were included in this study. Nine influencing factors related to aspiration were extracted for Meta-analysis. The Meta-analysis results showed that the three influencing factors that caused aspiration in neurocritical care patients were stroke history (OR=5.03, 95%CI, 2.71 to 9.32, P < 0.000 01), National Institutes of Health Stroke Scale (NIHSS) score >10 (OR=3.35, 95%CI, 1.75 to 6.42, P=0.000 3), and gastric residual volume >150 mL (OR=7.13, 95%CI, 2.55 to 9.96, P=0.001).
    Conclusion This study provides a scientific basis for clinical healthcare professionals to early identify high-risk patients for aspiration, take targeted intervention measures, and prevent the occurrence of aspiration.

     

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