Abstract: Frailty is prevalent in gastrointestinal cancer patients and severely affects their recovery. Frailty is reversible and its development can be prevented or reversed through interventions. This paper reviewed the measures, timing and places of interventions for frail gastrointestinal cancer patients, summarized effect evaluation indexes of interventions, and analyzed the hindering factors of interventions in frail gastrointestinal cancer patients, and proposed corresponding countermeasures, aiming to provide a reference for clinical interventions.