Abstract: Objective To analyze the effect of low-dose ropivacaine combined with sufentanil in patient-controlled epidural analgesia for labor. Methods A total of 120 puerperas were selected and divided into control group(n=60)and observation group(n=60)according to the order of hospital admission. The control group was treated by routine measures, while the observation group was treated with low-dose ropivacaine combined with sufentanil for analgesia. Analgesic effects were compared between the two groups. Results Before treatment, there was no significant difference in score of Visual Analogue Scale(VAS)between the two groups(P>0.05). At the time points of 10, 60, 120 minutes after treatment and orifice of uterus fully opening, the scores of VAS in the observation group were significantly lower than those in the control group(P<0.05). The time of each birth process in the observation group was significantly shorter than that in the control group(P<0.05). The Apgar score and the modified Bromage score of the newborns in the observation group were significantly higher than those in the control group(P<0.05). The ratio of pregnant women with oxytocin administration in the observation group was significantly lower than that in the control group(P<0.05). There were no significant differences in the incidence of fetal distress and postpartum hemorrhage between the two groups(P>0.05). The incidence of adverse events was 5.00% in the observation group, which showed no significant difference when comparing with 6.67% in the control group(P>0.05). Conclusion Application of low-dose ropivacaine combined with sufentanil in patient-controlled epidural analgesia for labor can significantly improve delivery outcome, relieve labor pain and shorten the time of labor process.