Analysis in characteristics of asymptomatic infection patients with coronavirus disease 2019 in Yangzhou City of Jiangsu Province
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摘要: 目的 分析扬州市新型冠状病毒肺炎(COVID-19)无症状感染者的流行病学特征。 方法 以扬州市2020年1月21日—2月29日发现的COVID-19无症状感染者为研究对象,收集流行病学、实验室检测、暴露情况等资料。 结果 扬州市14例COVID-19无症状感染者平均年龄为38.7岁,末次暴露到新型冠状病毒核酸检测阳性的平均时间为13.8 d, 92.9%为COVID-19确诊病例的暴露后感染, 85.7%为COVID-19确诊病例的家庭成员、亲戚等密切接触者。 结论 COVID-19无症状感染者以青壮年为主,主要来源于COVID-19确诊病例的密切接触者排查和聚集性疫情调查。及时开展密切接触者的排查和采样,规范密切接触者的管理,能减少COVID-19无症状感染者可能造成的疫情扩散,减少重症、危重症病例。COVID-19无症状感染者解除医学观察后,需开展2~4周的健康监测。Abstract: Objective To analyze epidemiological characteristics of the asymptomatic infection patients with coronavirus disease 2019(COVID-19)in Yangzhou City. Methods The asymptomatic infection patients with COVID-19 from 21 January to 29 February 2020 in Yangzhou City were selected as subjects, and their epidemiological materials, laboratory test results and exposure condition were collected. Results Totally 14 asymptomatic infection cases with COVID-19 were enrolled in this study, their average age was 38.7 years old, the mean time from last exposure to positive result of nucleic acid test was 13.8 days, 92.9% of them were infected after exposure to the confirmed cases, and 85.7% of them were the relatives or family members of the confirmed cases. Conclusion Most of asymptomatic infection cases with COVID-19 are young adults, and they are mainly infected due to close contacts of confirmed cases after screening and cluster epidemic investigation. Timely screening and sampling for close contacts can reduce the spread of epidemics due to the asymptomatic infection cases with COVID-19, and reduce the occurrence of severe and critical cases. For the asymptomatic infection cases with COVID-19, a health monitoring of 2 to 4 weeks should be implemented after release of medical observation.
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中华人民共和国国家卫生健康委员会. 国家卫生健康委办公厅关于印发新型冠状病毒肺炎防控方案(第五版)的通知[EB/OL].(2020-02-21)[2020-02-22]. http: //www. gov. cn/zhengce/zhengceku/2020-02/22/content_5482010.htm. 中华人民共和国国家卫生健康委员会. 关于印发《新型冠状病毒感染的肺炎诊疗方案(试行第五版)》的通知[EB/OL].(2020-02-05)[2020-02-21]. http: //www.nhc.gov.cn/yzygj/s7653p/202002/3b09b894ac9b4204a79db5b8912d4440.shtml. 中华预防医学会新型冠状病毒肺炎防控专家组. 新型冠状病毒肺炎流行病学特征的最新认识[J]. 中国病毒病杂志, 2020, 10(2): 81-85.
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