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彩色多普勒超声评价血塞通对尘肺肺心病患者心脏肺动脉压力的影响

Effect of Xuesai Tong on cardiac pulmonary artery pressure in pneumoconiosis patients with pulmonary heart disease evaluated by color Doppler ultrasonography

    摘要
  • 摘要:
      目的  采用彩色多普勒超声评价血塞通对尘肺肺心病患者心脏肺动脉压力的影响。
      方法  选取60例尘肺肺心病患者作为研究对象，采用随机数字表法将其分为血塞通组与常规组，各30例。常规组采用常规对症治疗，血塞通组在常规组基础上加用血塞通进行治疗，2组患者均连续治疗2周。比较2组患者治疗前后的肺动脉收缩压(SPAP)、血液流变学指标、血气分析指标和临床疗效、不良反应发生情况。
      结果  血塞通组的临床治疗有效率高于常规组，差异有统计学意义(P < 0.05); 治疗后，血塞通组患者的SPAP、全血高切黏度、全血低切黏度、血浆黏度、动脉血二氧化碳分压低于常规组，动脉血氧分压高于常规组，差异均有统计学意义(P < 0.05)。
      结论  采用血塞通治疗的尘肺肺心病患者的彩色多普勒超声检查结果显示，血塞通能够有效改善患者的血液流变学指标、SPAP及临床症状，且具有较高的安全性。

     

    Abstract:
      Objective  To evaluate the effect of Xuesai Tong on pulmonary artery pressure of heart in pneumoconiosis patients with pulmonary heart disease evaluated by color Doppler ultrasound.
      Methods  Sixty pneumoconiosis patients with pulmonary heart disease were selected as study subjects, and were divided into Xuesai Tong group and routine group by random number table method, with 30 cases in each group. The routine group was treated with conventional symptomatic treatment. The Xuesai Tong group was treated with Xuesai Tong on the basis of the routine group. Both groups were treated continuously for 2 weeks. Pulmonary arterial systolic pressure (SPAP), hemorheological indicators, blood gas analysis, clinical efficacy, and adverse reactions were compared between the two groups before and after treatment.
      Results  The clinical treatment of Xuesai Tong group was higher, SPAP, whole blood viscosity(high shear, low shear), plasma viscosity, arterial blood carbon dioxide partial pressure were lower, and the arterial oxygen partial pressure was higher than that in the conventional group, and the differences were statistically significant (P < 0.05).
      Conclusion  Color Doppler ultrasonography of pneumoconiosis patients with pulmonary disease treated with Xuesai Tong shows that Xuesai Tong can effectively improve the hemorheological index, SPAP and clinical symptoms.

     

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