进展性脑梗死危险因素及血清促炎性细胞因子水平研究

刘东玲

刘东玲. 进展性脑梗死危险因素及血清促炎性细胞因子水平研究[J]. 实用临床医药杂志, 2013, (3): 88-90. DOI: 10.7619/jcmp.201303028
引用本文: 刘东玲. 进展性脑梗死危险因素及血清促炎性细胞因子水平研究[J]. 实用临床医药杂志, 2013, (3): 88-90. DOI: 10.7619/jcmp.201303028
LIU Dongling. Progressive cerebral infarction risk factors and serum proinflammatory cytokine level research[J]. Journal of Clinical Medicine in Practice, 2013, (3): 88-90. DOI: 10.7619/jcmp.201303028
Citation: LIU Dongling. Progressive cerebral infarction risk factors and serum proinflammatory cytokine level research[J]. Journal of Clinical Medicine in Practice, 2013, (3): 88-90. DOI: 10.7619/jcmp.201303028

进展性脑梗死危险因素及血清促炎性细胞因子水平研究

基金项目: 中国高校医学期刊临床专项资金
详细信息
  • 中图分类号: R742

Progressive cerebral infarction risk factors and serum proinflammatory cytokine level research

  • 摘要: 目的 探讨进展性脑梗死患者危险因素及血清白介素-1β(IL-1β)、白介素-6(IL-6)水平.方法 入选患者为本院帐治的急性期脑梗死患者80例,包括非进展性脑梗死患者33例(非进展组)和进展性脑梗死患者47例(进展组).另选取同期来本院健康体检中心体检的40例患者作为对照组.检测各组患者生化指标;酶联免疫吸附法(Elisa)检测患者血清IL-1β、IL-6水平.结果 进展组患者空腹血糖(GLU)、血浆纤维蛋白原(FIB)、血清同型半胱氨酸(Hcy)水平明显高于非进展组.进展组和非进展组患者血清IL-1β、IL-6水平明显高于对照组.进展组患者血清IL-1β、IL-6水平明显高于非进展组、进展组计算机断层扫描(CT)早期异常表现发生率、大面积脑梗死发生率均明显高于非进展组.结论 高血糖、高纤维蛋白原血症、高同型半胱氨酸血症为进展性脑梗死的危险因素.血清IL-1β、IL-6水平对进展性脑梗死发生有早期预警意义.
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出版历程
  • 发布日期:  2013-05-22

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