不同选择性环氧合酶抑制剂对瑞芬太尼麻醉后痛觉过敏的影响

周德祥, 熊双宝, 熊雄

周德祥, 熊双宝, 熊雄. 不同选择性环氧合酶抑制剂对瑞芬太尼麻醉后痛觉过敏的影响[J]. 实用临床医药杂志, 2013, (3): 52-54,60. DOI: 10.7619/jcmp.201303016
引用本文: 周德祥, 熊双宝, 熊雄. 不同选择性环氧合酶抑制剂对瑞芬太尼麻醉后痛觉过敏的影响[J]. 实用临床医药杂志, 2013, (3): 52-54,60. DOI: 10.7619/jcmp.201303016
ZHOU Dexiang, XIONG Shuangbao, XIONG Xiong. Effect of different selective cyclooxygenase inhibitors on remifentanil-induced hyperalgesia[J]. Journal of Clinical Medicine in Practice, 2013, (3): 52-54,60. DOI: 10.7619/jcmp.201303016
Citation: ZHOU Dexiang, XIONG Shuangbao, XIONG Xiong. Effect of different selective cyclooxygenase inhibitors on remifentanil-induced hyperalgesia[J]. Journal of Clinical Medicine in Practice, 2013, (3): 52-54,60. DOI: 10.7619/jcmp.201303016

不同选择性环氧合酶抑制剂对瑞芬太尼麻醉后痛觉过敏的影响

详细信息
  • 中图分类号: R614

Effect of different selective cyclooxygenase inhibitors on remifentanil-induced hyperalgesia

  • 摘要: 目的 探讨不同选择性环氧合酶抑制剂对瑞芬太尼麻醉后痛觉过敏的影响.方法 选择瑞芬太尼维持的全麻下行全子宫切除术的患者60例,根据麻醉诱导前15 min用药不同分为2组,A组30例给予帕瑞昔布钠40 mg,B组30例给予酮咯酸氨丁三醇30 mg,观察术后15、30 min的疼痛评分和术后4、8、12、24 h的疼痛评分,病人自控镇痛(PCA)按压次数、镇痛药物消耗量.结果 A组在术后15 min疼痛评分小于B组(P<0.05);术后4h内A组的镇痛药物消耗量和PCA按压次数均少于B组(P<0.05).结论 麻醉诱导前给予帕瑞昔布钠相比酮咯酸氨丁三醇能更有效地抑制瑞芬太尼所致的痛觉过敏.
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出版历程
  • 发布日期:  2013-05-22

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